What is it used for?
Traditional medicine[ edit ] Common St. John's wort has long been used in herbalism and folk medicine. Folk usages included oily extract "St. John's oil" and Hypericum snaps. Hypericum perforatum is a common species and is grown commercially for use in herbalism and traditional medicine.
John's wort in the treatment of depression owing to limitations in the available evidence base, including large variations in efficacy seen in trials performed in German-speaking relative to other countries.
In GermanySt. John's wort may be prescribed for mild to moderate depression, especially in children and adolescents. John's wort for mild and moderate depression was better than placebo for improving depression symptoms, and comparable to antidepressant medication.
John's wort can interact in dangerous, sometimes life-threatening ways with a variety of prescribed medicines.
This can lead to visual sensitivity to visible and ultraviolet light and to sunburns in situations that would not normally cause them. John's wort can interfere with the effects of many prescription medicinesincluding birth control pillscyclosporinedigoxinHIV drugscancer medications including irinotecanand warfarin.
John's wort is discouraged for those with bipolar disorder. There is concern that people with bipolar depression taking St. John's wort may be at a higher risk for mania. This drug-metabolizing enzyme induction results in the increased metabolism of certain drugs, leading to decreased plasma concentration and potential clinical effect.
There is strong evidence that the mechanism of action of these interactions is activation of the pregnane X receptor. Increased P-glycoprotein expression results in decreased absorption and increased clearance of certain drugs, leading to lower plasma concentrations and impaired clinical efficacy.St.
John’s wort (Hypericum perforatum) is a flowering plant. The flowers are used to make liquid extracts, pills, and teas. The popular herbal therapy is often used to ease symptoms of depression. St. John's wort is a plant with yellow, star-shaped flowers and five petals that grows in Europe, North and South America, Australia, New Zealand, and Eastern Asia.
The plant grows in sunny, well. Hypericum perforatum, known as perforate St John's-wort, common Saint John's wort and St John's wort, is a flowering plant in the family Hypericaceae. It is believed to be a medicinal herb with antidepressant activity, although high-quality clinical evidence for such effects is kaja-net.com: Hypericaceae.
Medical uses St. John's wort has been used for hundreds of years in folk medicine, especially for healing wounds.
It was used for "driving out the inner devil" in medieval times. A flowering plant, St. John's wort (Hypericum perforatum) was named because the bright yellow flowers were said to bloom for the first time around St.
John the Baptist's kaja-net.com word "wort" means "plant" in . Increasing serotonin with St. John’s wort or drug therapy can benefit both mood and pain perception. Hypericum essential oil applied topically is .